The Crosbie Lab- UCLA Duchenne Muscular Dystrophy Research Center

Peter Angela K, Ko Christopher Y, Kim Michelle H, Hsu Nigel, Ouchi Noriyuki, Rhie Suhn, Izumiya Yasuhiro, Zeng Ling, Walsh Kenneth, Crosbie Rachelle H (2009) Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy. Human molecular genetics 18(2), 318-27. [link]

Peter Angela K, Marshall Jamie L, Crosbie Rachelle H (2008) Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex. The Journal of cell biology 183(3), 419-27. [link]

Bekker Janine M, Colantonio Jessica R, Stephens Andrew D, Clarke W Thomas, King Stephen J, Hill Kent L, Crosbie Rachelle H (2007) Direct interaction of Gas11 with microtubules: implications for the dynein regulatory complex. Cell motility and the cytoskeleton 64(6), 461-73. [link]

Peter Angela K, Miller Gaynor, Crosbie Rachelle H (2007) Disrupted mechanical stability of the dystrophin-glycoprotein complex causes severe muscular dystrophy in sarcospan transgenic mice. Journal of cell science 120(Pt 6), 996-1008. [link]

Miller Gaynor, Wang Emily L, Nassar Karin L, Peter Angela K, Crosbie Rachelle H (2007) Structural and functional analysis of the sarcoglycan-sarcospan subcomplex. Experimental cell research 313(4), 639-51. [link]

Peter Angela K, Crosbie Rachelle H (2006) Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway. Experimental cell research 312(13), 2580-91. [link]

Colantonio Jessica R, Bekker Janine M, Kim Sarah J, Morrissey Kari M, Crosbie Rachelle H, Hill Kent L (2006) Expanding the role of the dynein regulatory complex to non-axonemal functions: association of GAS11 with the Golgi apparatus. Traffic (Copenhagen, Denmark) 7(5), 538-48. [link]

Miller Gaynor, Peter Angela K, Espinoza Erica, Heighway Jim, Crosbie Rachelle H (2006) Over-expression of Microspan, a novel component of the sarcoplasmic reticulum, causes severe muscle pathology with triad abnormalities. Journal of muscle research and cell motility 27(8), 545-58. [link]

Yi Christopher E, Bekker Janine M, Miller Gaynor, Hill Kent L, Crosbie Rachelle H (2003) Specific and potent RNA interference in terminally differentiated myotubes. The Journal of biological chemistry 278(2), 934-9. [link]

Crosbie Rachelle H, Barresi Rita, Campbell Kevin P (2002) Loss of sarcolemma nNOS in sarcoglycan-deficient muscle. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 16(13), 1786-91. [link]

Crosbie Rachelle H, Dovico Sherri A, Flanagan Jason D, Chamberlain Jeffrey S, Ownby Charlotte L, Campbell Kevin P (2002) Characterization of aquaporin-4 in muscle and muscular dystrophy. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 16(9), 943-9. [link]

Crosbie, R. H., Barresi, R., and K.P. Campbell (2002) Loss of Sarcolemma nNOS in Sarcoglycan-Deficient Muscle FASEB J. 16, 1786-1791. [link]

Crosbie RH, Dovico SA, Flanagan JD, Chamberlain JS, Ownby CL, Campbell KP (2002) Characterization of aquaporin-4 in muscle and muscular dystrophy. FASEB J. 16(9), 943-9. [link]

Crawford GC, Faulkner JA, Crosbie RH, Campbell KP, Froehner SC, Chamberlain JS (2000) Assembly of the Dystrophin Associated Protein Complex Does Not Require the Dystrophin C-terminal Domain. J. Cell Biol. 150, 1411-1422.

Crosbie RH et al. (2000) Molecular and Genetic Characterization of Sarcospan:Insights into Sarcoglycan-Sarcospan Domains. Hum. Mol. Genet. 9, 2019-2027. [link]

Crosbie RH (2000) News and Views: NO Vascular Control in Duchenne Muscular Dystrophy. Nature Med. 7, 27-29.

Holt KH, Crosbie RH, Venzke DP, Campbell KP (2000) Biosynthesis of dystroglycan: processing of a precursor propeptide. FEBS letters. 468(1), 79-83. [link]

Crosbie RH, Lebakken CS, Holt KH, Venzke DP, Straub V, Lee JC, Grady RM, Chamberlain JS, Sanes JR, Campbell KP (1999) Membrane targeting and stabilization of sarcospan is mediated by the sarcoglycan subcomplex. J. Cell Biol. 145(1), 153-65. [link]

Crosbie RH, Yamada H, Venzke DP, Lisanti MP, Campbell KP (1998) Caveolin-3 is Not an Integral Component of the Dystrophin-Glycoprotein Complex. FEBS Lett. 427, 279-282.

Crosbie RH, Straub V, Yun HY, Lee JC, Rafael JA, Chamberlain JS, Dawson VL, Dawson TM, Campbell KP (1998) mdx muscle pathology is independent of nNOS perturbation. Hum. Mol. Genet. 7(5), 823-9. [link]

Duclos F, Straub V, Moore SA, Venzke DP, Hrstka RF, Crosbie RH, Durbeej M, Lebakken CS, Ettinger AJ, van der Meulen J, Holt KH, Lim LE, Sanes JR, Davidson BL, Faulkner JA, Williamson R, Campbell KP (1998) Progressive Muscular Dystrophy in alpha-Sarcoglycan Deficient Mice. J. Cell Biol. 142, 1461-1471.

Crosbie RH, Heighway J, Venzke DP, Lee JC, Campbell KP (1997) Sarcospan: The 25kDa Transmembrane Component of the Dystrophin-Glycoprotein Complex. J. Biol. Chem. 272, 31221-31224.

Campbell KP, Crosbie RH (1996) NEWS AND VIEWS: Utrophin to the Rescue. Nature 384, 308-309.

Crosbie RH, Chalovich JM, Reisler E (1995) Flexation of caldesmon: effect of conformation on the properties of caldesmon. J. Muscle Res. Cell Mot. 16(5), 509-18. [link]

Crosbie RH, Miller C, Cheung P, Goodnight T, Muhlrad A, Reisler E (1994) Structural connectivity in actin: effect of C-terminal modifications on the properties of actin. Biophysical J. 67(5), 1957-64. [link]

Crosbie RH, Miller C, Chalovich JM, Rubenstein PA, Reisler E (1994) Caldesmon, N-terminal yeast actin mutants, and the regulation of actomyosin interactions. Biochemistry. 33(11), 3210-6. [link]

Crosbie RH, Chalovich JM, Reisler E (1992) Interaction of caldesmon and myosin subfragment 1 with the C-terminus of actin. Biochem. Biophys. Res. Comm. 184(1), 239-45. [link]

Crosbie R, Adams S, Chalovich JM, Reisler E (1991) The interaction of caldesmon with the COOH terminus of actin. J. Biol. Chem. 266(30), 20001-6. [link]