Albuterol References

Use of Albuterol in treating DMD

1. del Barrio, A.S., et al., Effects of the beta-adrenergic agonist salbutamol and its withdrawal on protein metabolism of lambs. Ann Nutr Metab 1995; 39:(5): p. 317-24.

2. Carter, W.J. and M.E. Lynch, Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats. Metabolism 1994; 43:(9): p. 1119-25.

3. Carbo, N., et al., Comparative effects of beta2-adrenergic agonists on muscle waste associated with tumour growth. Cancer Lett 1997; 115:(1): p. 113-8.

4. Costelli, P., et al., Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway. J Clin Invest 1995; 95:(5): p. 2367-72.

5. Moore, N.G., G.G. Pegg, and M.N. Sillence, Anabolic effects of the beta 2-adrenoceptor agonist salmeterol are dependent on route of administration. Am J Physiol 1994; 267:(3 Pt 1): p. E475-84.

6. Petrou, M., et al., Clenbuterol induces hypertrophy of the latissimus dorsi muscle and heart in the rat with molecular and phenotypic changes. Circulation 1995; 92:(9 Suppl): p. II483-9.

7. Prather, I.D., et al., Clenbuterol: a substitute for anabolic steroids? Med Sci Sports Exerc 1995; 27:(8): p. 1118-21.

8. Rehfeldt, C., et al., Effect of clenbuterol on growth, carcass and skeletal muscle characteristics in broiler chickens. Br Poult Sci 1997; 38:(4): p. 366-73.

9. Schiavetta, A.M., et al., Adipose tissue cellularity and muscle growth in young steers fed the beta-adrenergic agonist clenbuterol for 50 days and after 78 days of withdrawal. J Anim Sci 1990; 68:(11): p. 3614-23.

10. Van der Heijden, H.F., et al., Effects of salbutamol on rat diaphragm contractility. J Appl Physiol 1996; 81:(3): p. 1103-10

11. Young, O.A., et al., The role of insulin-like growth factor I in clenbuterol-stimulated growth in growing lambs. J Anim Sci 1995; 73:(10): p. 3069-77.

12. Zemen, R.J., R. Ludemann, and J.D. Etlinger, Clenbuterol, a ß2-agonist, retards atrophy in denervated muscles. Am J Physiol 1987; 252:(Endocrinol. metab. 15): p. E152-E155.

13. Zhou, G.H. and Z.K. Han, Effects of dietary supplementation of beta 2-adrenergic agonist clenbuterol on carcase characteristics and some metabolites in ducks. Br Poult Sci 1994; 35:(3): p. 355-61.

14. Martineau, L., et al., Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men [published erratum appears in Clin Sci 1993 Jun;84(6):following XX]. Clin Sci (Colch) 1992; 83:(5): p. 615-21.

15. Martineau, L., et al., Clenbuterol, a beta 2-adrenergic agonist, reverses muscle wasting due to scald injury in the rat. Burns 1993; 19:(1): p. 26-34.

16. Maltin, C.A., et al., Clenbuterol, a beta-adrenoceptor agonist, increases relative muscle strength in orthopaedic patients. Clin Sci (Colch) 1993; 84:(6): p. 651-4.

17. Caruso, J.F., et al., The effects of albuterol and isokinetic exercise on the quadriceps muscle group. Med Sci Sports Exerc 1995; 27:(11): p. 1471-6.

18. Dupont-Versteegden, E.E., Exercise and clenbuterol as strategies to decrease the progression of muscular dystrophy in mdx mice. J Appl Physiol 1996; 80:(3): p. 734-41.

19. Dupont-Versteegden, E.E., M.S. Katz, and R.J. McCarter, Beneficial versus adverse effects of long-term use of clenbuterol in mdx mice. Muscle Nerve 1995; 18:(12): p. 1447-59.

20. Rothwell, N., J, and M.J. Stock, Modification of body composition by clenbuterol in normal and dystrophic (mdx) mice. Bioscience Reports 1985; 5:(: p. 755-760.

21. Hayes, A. and D.A. Williams, Contractile properties of clenbuterol-treated mdx muscle are enhanced by low-intensity swimming. J Appl Physiol 1997; 82:(2): p. 435-9.

22. Hayes, A. and D.A. Williams, Long-term clenbuterol administration alters the isometric contractile properties of skeletal muscle from normal and dystrophin-deficient mdx mice. Clin Exp Pharmacol Physiol 1994; 21:(10): p. 757-65.

23. Zeman, R.J., Y. Zhang, and J.D. Etlinger. Clenbuterol, a beta 2-agonist, retards wasting and loss of contractility in irradiated dystrophic mdx muscle. Am J Physiol 1994; 267:(3 Pt 1): p. C865-8.

 

Role of the immune system in dystrophinopathy

24. Cai, B. M.J. Spencer, G. Nakamura, L. Tseng-Ong and J.G. Tidball. Eosinophilia of dystrophin-deficient muscle is promoted by perforin-mediated cytotoxicity by T cell effectors. American Journal of Pathology, 2000 May, 156(5):1789-96.

25. Gussoni, E., G.K. Pavlath, R.G. Miller, M.A. Miller, M.A. Panzara, M. Posell, H.M. Blau and L. Steinman. 1994. Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. Journal of Immunology 153: 4798-4805.

26. Ohtsuka, Y., K. Udaka, Y. Yamashiro, H. Yagita and K. Okumura. 1998. Dystrophin acts as a transplantation rejection antigen in dystrophin-deficient mice: implication for gene therapy. Journal of Immunology 160: 4635-4640.

27. Rando, T.A., M-H. Disatnik, Y. Yu and A. Franco. 1998. Muscle cells from mdx mice have an increased susceptibiltiy to oxidative stress. Neuromuscular Disorders 8: 14-21.

28. Spencer, M. J., C.M. Walsh, K.A. Dorshkind, E. Montecino Rodriguez and J.G. Tidball. 1997. Myonuclear apoptosis in dystrophic mdx muscle occurs by perforin-mediated cytotoxicity. Journal of Clinical Investigation 99: 2745-2751.

29. Spencer, MJ, M.W. Marino, and W.M. Winckler. Altered pathological progression of diaphragm and quadriceps muscle in TNF-deficient, dystrophin-deficient mice. Neuromuscular Disorders, 2000 Dec, 10(8):612-9.

30. Spencer, MJ, E. Montecino-Rodriguez, K. Dorshkind, and J.G. Tidball. Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle. Clinical Immunology, 2001 Feb, 98(2):235-43.

31. Spencer, M.J. and J.G. Tidball. Do immune cells contribute to the pathology of dystrophin-deficient myopathies? Neuromuscular Disorders, 2001. (in press).

32. Wehling, M., M.J. Spencer and J.G. Tidball. A nitric oxide transgene ameliorates muscular dystrophy in mdx mice. Journal of Cell Biology, 2001. (in press)

 

 

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